It used to work. Was left connected and then didn't work. I'm unsure if the misses didn't knock it off the desk. Figure new cables would be the cheapest/easiest test. I have 2 carts and neither worked with it.

It's a parallel cable, not a serial cable. If you have somehow connected it through a cable to something marked as a serial port on the computer, you've probably blown the transferer.
Did this particular cable use to work before? Did you switch to a new computer lately? Muck around with the BIOS settings? If so, those are more likely suspects to begin with.
If you get a new cable, make sure it's a 1-1 (one to one) cable, not a Laplink cable.

Columbus, Indiana...... need to update that, sorry.

Where are you located?

Yeah for some reason I am getting an error 452 and am going to try and get a cheap cable. If you have one and are reluctant about selling it cheap, just remember I love you.