I'm not super experienced with modern DAWs, so I can't answer your question well, but I think you can just use it as an external midi slave in a way similar to how you would use a MIDIbox FM.
Well, I managed to crash the shit out of my PentiumIII 98SE laptop trying to get the MPU-401 support working. I don't know why the lappy didn't like it. It's kind of a moot point anyway, it doesn't have a standard game port on it… I'm not sure how I'd go about connecting my controller to it anyway.
It's all good, though. I have a Yamaha YMF7xx card in the mail, and my XP machine is going to get a 98SE partition, so we'll be putting the FM in Funky Music shortly~~